Below you will find pages that utilize the taxonomy term “Vitamins”
Article Criticism (Focus Online)
Are you flushing money—and your health—down the drain
with vitamins? Stick around as we uncover shocking truths about a recent article on supplements that gets it all wrong! An article from Focus Online claims to reveal which vitamins are worth it and which are just making your urine expensive. But here’s the catch—it’s riddled with misinformation, outdated science, and alarmist advice. Let’s break it down!
Outdated Perspective on Nutritional Content
- Decreased Nutritional Value in Modern Foods: The article assumes a “well-balanced diet” today provides sufficient nutrients, but it ignores substantial research indicating that modern agricultural practices, soil depletion, and food processing have reduced the nutrient content of many foods compared to 50 years ago. For example:
- Evidence: Studies have documented declines in magnesium, calcium, and vitamins in crops due to soil depletion and high-yield cultivars (Mayer et al., 2021) and shifts from natural to chemical farming (Bhardwaj et al., 2024).
- Nutrient dilution occurs in crops bred for higher yields, reducing essential minerals in food (Davis, 2009).
Lack of References and Evidence
- No Scientific Citations: The article refers to studies and findings (e.g., a large US study, a metanalysis, and trials on Vitamin A or Vitamin E) but fails to provide proper citations or hyperlinks to these studies. This makes it impossible for readers to verify claims or delve deeper into the research.
- Unsubstantiated Claims: While it mentions potential harms of over-supplementation (e.g., increased cancer risk, kidney stones, or liver damage), these are anecdotal without detailed data or named studies.
- Generalizations like “Vitamin C doesn’t protect against colds” lack nuance. Specific research supports modest benefits of Vitamin C in reducing cold duration for certain populations and related to that also improved recovery from severe physical exercise Hemilä and Chalker, 2013.
Misrepresentation of Vitamin B12
- B12 Source Error: The article perpetuates a common misconception by implying that animal products are the “natural” source of Vitamin B12. In reality, Vitamin B12 is produced exclusively by bacteria and archaea, not animals Fang et al., 2017. Animals accumulate B12 by consuming bacteria-laden soil, water, or through bacterial synthesis in their digestive systems. This point is particularly relevant for:
- Modern farming practices that eliminate natural exposure to bacteria (e.g., sterilized feed and water), often necessitating the fortification of animal feed with synthetic B12.
- Plant-based eaters who may miss out on B12 due to the lack of natural bacterial sources in modern, sanitized food systems.
- In summary, the more contaminated our food is with bacteria, the higher the B12 amount in the food. It could make one cringe to hear that animal products are high in B12 (from fecal contamination during processing?).
- Misleading Statement on Veganism: While the article acknowledges that vegans require B12 supplementation, it oversimplifies the issue by ignoring that even non-vegans can be at risk. For instance:
- Older adults often experience reduced B12 absorption due to lower stomach acid production, regardless of diet. Evidence: Absorption issues affect over 20% of adults over 60 (Hepperly & Seidel, 2018).
- Individuals with gastrointestinal disorders (e.g., Crohn’s disease or celiac disease) or those on certain medications (e.g., proton-pump inhibitors) may also struggle to absorb B12.
- Fun fact: Bacteria in the human gut also produce Vitamin B12. Unfortunately, it is produced too far down in the gut, and we cannot take it up from the gut anymore.
Failure to Address Real-World Dietary Challenges
- Lifestyle and Accessibility: The article doesn’t consider the challenges many people face in consistently achieving a “well-balanced” diet:
- Time constraints and socioeconomic factors often lead to reliance on processed foods, which may lack sufficient micronutrients.
- Seasonal availability of fresh produce can impact dietary diversity and nutrient intake.
- Individual Variability: It fails to address how individual metabolic and genetic factors (e.g., MTHFR gene mutations affecting folate metabolism) may necessitate supplementation for optimal health, even in those eating varied diets.
- A global meta-analysis highlights the widespread deficiencies of essential nutrients like Vitamin A and folate Herrero et al., 2017.
Limited Relevance for Consumers
- Generalized Advice: Statements like “most people do not need supplements if they eat a balanced diet” are overly broad. They fail to address scenarios where individuals may have unique dietary restrictions, medical conditions, or lifestyle factors that necessitate supplementation.
- Lack of Clarity on Dosages: While the article warns about overdosage risks, it doesn’t provide actionable details such as safe dosage ranges, nor does it refer to official recommendations like those from the EFSA (European Food Safety Authority) or BfR (German Federal Institute for Risk Assessment).
- Simplistic Categorization: Grouping vitamins into “good” and “bad” categories oversimplifies a complex topic. For example:
- Vitamin C is dismissed, but for individuals with specific deficiencies or increased needs (e.g., smokers or the elderly), supplementation might be warranted.
- Multivitamins are dismissed wholesale, ignoring specific populations who might benefit, like those with malabsorption issues.
Broader Context on Supplements
- General Criticism Without Nuance: While the article criticizes over-supplementation, it overlooks the critical role supplements can play in specific scenarios:
- Pregnancy, lactation, and aging increase nutrient requirements that may not always be met through food alone.
- Certain supplements, such as iodine in regions with low natural iodine in the soil, have been instrumental in addressing public health issues.
- Failure to Differentiate Synthetic vs. Natural Sources: For example:
- The efficacy and bioavailability of synthetic versus natural forms of vitamins (e.g., folic acid vs. methylfolate) are not discussed.
- A prominent example is Vitamin E, which is actually eight different compounds. One of them Alpha-tocopherol exists as one stereoisomer in nature but, when produced chemically, has several stereoisomers. Remember Contagan? The issue was that we couldn’t or didn’t separate the unnatural stereoisomers. Failure to understand such issues leads to severe outcomes (Contergan) or outcomes we do not yet understand (Vitamin E).
Missed Opportunities for Actionable Guidance
- No Practical Recommendations: The article fails to guide readers on identifying a potential deficiency or when to consult a doctor. For example, it could suggest regular blood tests to assess vitamin levels. Blood testing and physician consultations are recommended to avoid both deficiencies and excesses Example.
- Overlooked Populations: The nuanced needs of subpopulations (e.g., older adults, people with darker skin living in low-sunlight regions, or those with restrictive diets) are ignored. For instance, MTHFR mutations affect folate metabolism, requiring targeted intervention Zarembska et al., 2023.
Misleading and Alarmist Tone
- Fear-Based Messaging: The article leans heavily on scare tactics, such as phrases like “teuren Urin” (expensive urine) and “im schlimmsten Fall schaden” (worst case, harm your health). This tone can alienate readers rather than educate them.
- One-Sided Perspective: While it critiques unnecessary supplementation, it does not adequately acknowledge the prevalence of deficiencies in certain groups or provide balanced views on supplements’ potential benefits.
Suggestions for Improvement
To correct these issues, the article should:
Vitamin D Supplementation
Vitamin D, often called the “sunshine hormone,” plays a vital role in overall health. Many people in the Western world are deficient in it, but before deciding to supplement, it’s essential to test your blood levels (Calcifediol). This can help you understand whether supplementation is necessary and how much you need to reach optimal levels.
Key considerations include your current blood levels, lifestyle, UVB exposure, skin tone, BMI, and health conditions. Vitamin D3 (Cholecalciferol) is the preferred supplement form, as it is more effective than Vitamin D2. Individuals with higher BMIs or certain health conditions may require higher doses or specialized forms like Calcifediol or Calcitriol.
Ergocalciferol
Ergocalciferol (vitamin D2) is made by plants and is similar to Cholecalciferol (vitamin D3), but it’s less effective for humans. D3 is better at raising vitamin D levels and has stronger effects in the body, while D2 binds less efficiently to the vitamin D receptors.
Studies have shown that D3 is more effective at improving vitamin D stores and lowering parathyroid hormone. Though some medications use high doses of D2, newer research suggests D3 supplements are a better choice. Plants like mushrooms and algae produce D2 when exposed to UVB light, but D2 levels are much lower than D3 found in fatty fish, for example.
In summary, D2 is similar to D3 but provides less bang for the buck.
Vitamins
What is a vitamin? A vitamin is an organic compound that the human body requires in small amounts to carry out essential biochemical functions, such as metabolism, immune support, and cellular repair. Unlike other nutrients, vitamins cannot be synthesized by the body and must be obtained through diet or supplementation. This reliance on external sources highlights their crucial role in maintaining health and well-being.
Many vitamins have been found, with vitamin D being a historical misinterpretation. Deficiencies in vitamins do not necessarily equate to imminent death, but there will be some health repercussions. Below is a list of vitamins that you can follow once I add some information, which will take some time. Let’s first have a look at a very crude classification of vitamins into fat- and water-soluble ones.
Vitamin D Unit Converter
Vitamin D (Cholecalciferol) used to be measured in micrograms (mcg). At one point, international units were introduced (IU). Today, either or both IU and mcg are found on supplement labels. Sometimes, it is beneficial to know the amount in IU and the amount in mcg. Especially when you want to use the correct ratio of several vitamins simultaneously. An important example in this context would be the combination of vitamin D and vitamin K. While Cholecalciferol ensures that there is enough calcium in the blood, vitamin K is involved in bringing calcium to the correct location (bones). Calcification of soft tissues such as cartilage and arteries is definitely something no one wants. Therefore, both vitamins should be used together. How much of each is a discussion for another time. However, once you decide and settle on a ratio between vitamins D and K, you can use the below converter to ensure that you use the correct amounts.
Vitamin D Regulation
Calcitriol, the active form of vitamin D, is a powerful hormone that needs tight regulation in the body. It acts like a “key” that fits into specific “locks” (receptors) to manage important functions like calcium and phosphate balance. Too much or too little can cause harm, so the body carefully controls how much is made.
The body converts stored vitamin D (Calcifediol) into Calcitriol in the kidneys, but if Calcitriol levels get too high, enzymes slow down its production and break it down. Calcium and phosphate levels in the blood also help regulate this process.
Low calcium triggers the production of more Calcitriol, while high calcium or phosphate slows it down. Additionally, low phosphate increases Calcitriol, while high phosphate decreases it. These processes work together to maintain balance, ensuring proper calcium and phosphate levels in the blood.
If vitamin D stores are low, the body can’t produce enough Calcitriol, which can lead to health problems.
Calcitriol
The name Calcitriol (aka vitamin D) refers to a hormone that is produced via hydroxylation of Calcifediol in the human liver. Calcitriol is typically bound by the D-binding protein (DBP) but has a lower affinity DBP than Calcifediol but higher than Cholecalciferol. Calcitriol is the active form of the hormone and facilitates calcium uptake among a myriad of other functions, such as immune system-related ones.
Calciol
Cholecalciferol
For more technical details, read on.
Calcifediol
The name Calcifediol (aka vitamin D) refers to a hormone that is produced via hydroxylation of Cholecalciferol in the human liver. Calcifediol is typically bound to the D-binding protein (DBP) but can be unbound if there is not enough DBP. If unbound, it is typically degraded and excreted via the kidneys. When bound to DBP, Calcifediol is relatively stable and can circulate in the human blood for weeks. Unless it is converted to Calcitriol and used by downstream processes. If demand for Calcitriol is high, e.g., low calcium or challenges to the immune system, ‘stored’ Calcifediol is converted to Calcitriol quicker.
Vitamin D Solubility
Vitamin D, in fact a hormone, is said to be soluble in fat. Therefore, it has been cautioned, that too large an intake or production of D3 or more precisely Cholecalciferol can be dangerous since it could be stored in fat. Solubility is not that easy, especially when considering biological systems. First of, anything is soluble in anything to a varying degree. When saying D3 is fat soluble, we also need to consider that there are three different molecules that we mean when we say D3 (see vitamin D for a disambiguation).